County of Los Angeles
Department of Public Health
Acute Communicable Disease Control
313 N. Figueroa Street, Room 212
Los Angeles, CA 90012
Phone: (213) 240-7941
Fax: (213) 482-4856
E-Mail:acdc2@ph.lacounty.gov
Have questions about things like where to go for vaccinations or
other health care
services?
Call 2-1-1.
Adobe Reader
Note: PDF documents on this site were created using Adobe Acrobat 5.0 or later. If you are using an earlier version of Adobe Acrobat Reader (4.x or less), document functionality may be reduced.
Acute Communicable Disease Control
Hepatitis B, Perinatal
Hepatitis B is a vaccine-preventable disease transmitted through parenteral or mucous
membrane exposure to blood and other body fluids of individuals infected with the
hepatitis B virus (HBV). It is also transmitted from mother to infant during birth.
Within LAC, it is estimated that over 40% of infants born to hepatitis B surface
antigen (HBsAg) positive women will become infected without prophylaxis. An estimated
90% of infants who become infected by perinatal transmission develop chronic HBV
infection and up to 25% will die from chronic liver disease as adults. Hepatitis B
vaccination and one dose of hepatitis B immune globulin (HBIG), administered within
24 hours after birth, are 85–95% effective in preventing both HBV infection and the
chronic carrier state. Post-vaccination serologic testing is recommended 3–18 months
after completing immunoprophylaxis to verify vaccine success or failure. The
Immunization Program’s Perinatal Hepatitis B Prevention Program (PHBPP) conducts
case management of HBsAg-positive pregnant women, their newborns, and household
contacts.
Hepatitis B is a vaccine-preventable disease transmitted through parenteral or mucous
membrane exposure to blood and other body fluids of individuals infected with the
hepatitis B virus (HBV). It is also transmitted from mother to infant during birth.
Within LAC, it is estimated that over 40% of infants born to hepatitis B surface
antigen (HBsAg) positive women will become infected without prophylaxis. An estimated
90% of infants who become infected by perinatal transmission develop chronic HBV
infection and up to 25% will die from chronic liver disease as adults. Hepatitis B
vaccination and one dose of hepatitis B immune globulin (HBIG), administered within
24 hours after birth, are 85–95% effective in preventing both HBV infection and the
chronic carrier state. Post-vaccination serologic testing is recommended 3–18 months
after completing immunoprophylaxis to verify vaccine success or failure. The
Immunization Program’s Perinatal Hepatitis B Prevention Program (PHBPP) conducts
case management of HBsAg-positive pregnant women, their newborns, and household
contacts.
Flu surveillance and related disease updates for LA County
